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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of congenital cataract
ncRNA name hsa-miR-204
ncRNA Category miRNA
Disease name congenital cataract
Species Homo sapiens
Tissues/Cell_line lenses; human lens epithelial cell line HLE-B3
Methods RT-PCR, transfection, Western blot
Expression pattern down-regulated
Functional description The expression levels of miR-182, miR-204 and miR-124 differ between the central epithelium of transparent infant lens and congenital cataract, suggesting their involvement in the pathogenesis of congenital cataract. miR-204 may act via silencing Meis2 to regulate lens development and congenital cataract formation.
PubMed ID 28393025
Year 2017
Title Expression of lens-related microRNAs in transparent infant lenses and congenital cataract.
Drug-related ncRNA NO

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